具体描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用户评价
##看到在FDA调查员住的酒店装监听器真的看得我毛骨悚然，后面真的心疼baker和thakur。一个辛辛苦苦找fraudelence的证据后给出OAI，agency却为了指标downgrade to VAI，lift ban...一个为了正义做whistleblower，说因此导致妻离子散，家破人亡也不为过。 难道只要有药，就可以不论质量地给病人吃吗。 如果代表着最高标准的FDA都是这样让人心寒，我们还能相信谁。难道以后大家保命只能花巨额买brand-name吗.. 对lal，baker，thakur等战士表示敬意，对Katherine Eban在内的所有调查记者致以敬意。因为他们，我们才离真相越来越近。也因此看清了善与恶的对抗不过是以卵击石。一切正义行为在利益面前都是如此不堪一击。
评分##触目惊心，肺炎疫情期间看更有额外的感慨。关于天朝那一段估计中文版会删吧……
评分##做了心理建设还是很难相信这种肮脏勾当是广泛存在的，FDA的形式主义和无所作为也是视人命如草芥
评分##investigative journalism比侦探悬疑武侠都好读！本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics，后面读到drug resistance那段觉得也无所谓了，????大家一起玩完。
评分##优点是：1 故事精彩，特别是Ranbaxy部分 2 对仿制药的出现和问题的支出，在4+7时代尤其重要。缺点是：1 太多采访驱动，数据太少，导致面子太多里子不够 2 野心太大导致主线太散
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
评分##Generic drugs still have a long way to go
评分##做了心理建设还是很难相信这种肮脏勾当是广泛存在的，FDA的形式主义和无所作为也是视人命如草芥
评分##一个这么好的题材，被作者写得稀烂。故事非常散乱且冗长。有种所有我调查到的内容都要填进去的杂乱感。人物脸谱化，凡正面角色一定要讲到成长经历，父亲职业的影响，反面角色一定是生活奢迷，草菅人命，毫无道德可言。350字装不下我的吐槽。可能需要写一篇长评。。。。。。
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