A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin, by the prize-winning, bestselling author of Say Nothing
The Sackler name adorns the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis.
Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm.
Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. The brothers began collecting art, and wives, and grand residences in exotic locales. Their children and grandchildren grew up in luxury.
Forty years later, Raymond’s son Richard ran the family-owned Purdue. The template Arthur Sackler created to sell Valium—co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness—was employed to launch a far more potent product: OxyContin. The drug went on to generate some thirty-five billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die.
This is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful.
Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. It is a portrait of the excesses of America’s second Gilded Age, a study of impunity among the super elite and a relentless investigation of the naked greed and indifference to human suffering that built one of the world’s great fortunes.
##Take it with a pinch of salt. No, two pinches of salt.
評分##"If there was one thing, apart from donating money, that the Sacklers knew how to do, it was sell opioids." 看這書讓我感覺真心感覺FDA是個250,前一款opioid pain killer的專利期剛過,Sackler就發布一款新的止痛藥並聲稱比之前那款更加不會導緻上癮,FDA居然也能審批通過。而且一個傢族在作惡數個generation之後遭遇集體控訴還可以全身而退,完全沒有對個人的任何處決,甚至還能照樣帶走幾十個billion,資本對世界的控製真是可怕
評分##我以為Book 1的stereotypical老白男發傢史已經很讓人血壓飆升瞭,沒想到Book 2&3裡二代三代們的pathological-denial and accountability-avoiding真是歎為觀止的rage-inducing。我相信第一代進入製藥業的齣發點是好的,第二代發明oxycontin的齣發點是好的。但因為上市前的研究不足,以及aggressive advertising (no thanks to Arthur Sackler and his methods)導緻現在opioid crisis這傢人的作為 (or lack thereof)肯定是有直接關係的。書裡揭露齣有問題的不僅是這傢人,不僅是製藥業,不僅是資本,還有不作為的FDA、司法機構和法律漏洞
評分##真的是很勇敢很難得的一本書,作者在寫作的時候還在被人威脅。
評分##被The Sacklers的一係列操作驚呆瞭,玩轉FDA於掌心,獲得暴利,再用慈善之名洗白,最後再玩一齣宣告破産的金蟬脫殼,牛逼啊牛逼
評分##"A story about ambition, philanthropy, crime and impunity, the corruption of institutions, power and greed", well written! Philanthropy is different from charity. It is a business. 當Arthur Sackler第一次嚮大都會博物館"捐贈"的時候支付瞭館內已有"藏品"多年前的收購價,用它們的市價進行瞭報稅抵扣,不僅沒花錢,反倒掙瞭一筆,並冠名成功。 Sackler三兄弟年輕的時候是共産主義者,他們期望"help alleviate man‘s suffering." 他們傢族沒有人為廣告誤導造成的止痛藥濫用愧疚。
評分##第一部分arthur發傢史尤其精彩,可以說是page-turner。要是配一副family tree這種人物關係圖就更友好瞭。文筆很好(有用無用的詞匯和錶達又增加瞭!比如sunset做動詞,還有好笑的oxySacklers)。作者搜集並厘清那麼多資料和訪談,一邊還要對付sackler那邊的律師,最後匯總為一本五百多頁的書(有點太厚,說真心話)!後麵兩部分有點在看傲骨之戰的感覺,果然作者本身也是法律專業齣身(還娶瞭個律師老婆)。如同作者所言,這本書不會是有關這個傢族和鴉片藥物泛濫事件的最後一本書,還有很多未披露未公布的資料留待後來者分析。直到bring the whole truth to light.
評分##bad blood之後,又一本讓人倒抽一口涼氣的非虛構作品。從Arthur開創瞭醫藥營銷,到Richard將其發揚光大,再到David宣布破産搞瞭一齣金蟬脫殼,Sackler傢族可謂完成一齣前無古人後無來者的美國夢。不論是FDA,CDC,還是各州ag到DOJ,全都拿sackler沒辦法,資本對政治的侵襲能到何種程度,可見一斑。
評分##看得惡嚮膽邊生……真的太氣瞭……就實話講他們一開始說病人的疼痛不應該被忽視、應該推廣對疼痛的治療的時候我確實很同意,至少這個齣發點是沒錯的,但是可怕的是他們極度aggressive的營銷方式,以及東窗事發之後理直氣壯地撇清關係……另外我始終覺得醫療行業和教育行業,由於從業者和消費者的信息不對稱過於嚴重,甚至有一些權利上下遊倒置的感覺,因此這兩個行業的商業化是危險的、自由競爭是不利於消費者的,但是完全依靠(往往underfunded的)公費醫療、公立學校教育又遠遠不能滿足需求,這其中的矛盾實在是很難解決
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