Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##优点是:1 故事精彩,特别是Ranbaxy部分 2 对仿制药的出现和问题的支出,在4+7时代尤其重要。缺点是:1 太多采访驱动,数据太少,导致面子太多里子不够 2 野心太大导致主线太散
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##药店卖高价来研发药,不义者用仿制药赚钱,悲悯者用仿制药救人,穷人用仿制药来活命。现如今,仿制药己不能单纯用好或坏来形容,而是一个包含了不同人不同愿望的大锅,我只希望都多一份宽容,药店让穷人活命,富人帮药店筹款,不义者受制裁,穷人尽力帮药店……希望一切都变好...
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
评分##如果说“仿制药”这个名词曾经是一个陌生词,那么伴随着电影《我不是药神》的上映,仿制药这个词也走进了大众视野。仿制药一时间成为了同效、低价的代名词,对于“品牌药”高定价的口诛笔伐更是不曾消停。然而世界上并没有免费的午餐,同效药物之间的价格鸿沟是如何形成的?仿...
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##这本书像一个加长版bad blood 都是从上到下做假 不在意生产过程 该work的行业标杆FDA水土不服监管失灵 whistle blower心惊胆战地揭秘但是调查迟缓 可以感受到对global south的凝视 印象最深刻的是对whistle blower的比喻:大家都听说过可是没有人见过他们 说起仿制药的话题,相信绝大多数朋友第一时间想到的都是那部现象级的电影《我不是药神》的描写:效果和正牌药一模一样,往往都在印度那边生产,因为相关法律问题国内很难弄到…… 不过我对仿制药的印象却和那部电影不太一样,因为我的亲叔叔就患有慢粒细胞白血病,需要服用影片...
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