Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##如果說“仿製藥”這個名詞曾經是一個陌生詞,那麼伴隨著電影《我不是藥神》的上映,仿製藥這個詞也走進瞭大眾視野。仿製藥一時間成為瞭同效、低價的代名詞,對於“品牌藥”高定價的口誅筆伐更是不曾消停。然而世界上並沒有免費的午餐,同效藥物之間的價格鴻溝是如何形成的?仿...
評分 評分 評分##簡直是觸目驚心的一本書,4.5星,半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢,藥性與原廠藥不能相比就不說瞭,篡改僞造數據也不說瞭,製藥環境居然如此惡劣,而廠商以及質監局的態度又是如此的nonchalant,對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠,相關人員隻圖暴利而不把民眾的安全和性命當一迴事,最後卻也沒有得到法律製裁的種種事情實在是讓人發指!立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
評分##如短評所述,本書是令人震驚和恐懼的行業揭秘。對美國(也許和中國)而言,麵臨的是仿製藥的質量問題(甚至副作用)和價格惠民的矛盾。法律法規和管理辦法某種程度上激勵企業進行冒險和不道德行為,最終造成道德風險和逆嚮選擇。事實上,這一問題廣泛存在,無論是藥品,還是更...
評分 評分 評分 評分觸目驚心,我國石傢莊一傢藥企“上榜”,生産的無效頭孢在非洲緻兒童死亡,中文版裏不知能否保留
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